Collagen dressings are not all the same. When selecting an advanced wound care collagen dressing, consider the type and source of collagen, manufacturing process, cost-effectiveness, user-friendliness, and bioactive technology of the dressing. Bioactive collagen materials help stimulate different cells, provide an optimal moist wound healing environment while moving wounds towards a healing trajectory. Clinical data indicates collagen-based dressings may be capable of manipulating the wound biochemistry and targeting imbalances in wound chronicity.
Collagen plays a crucial role in every wound healing phase and is the novel triple helix protein molecule that forms the vital fragment within the extracellular matrix (ECM). In a perfect wound environment, these healing phases occur in an organized fashion (hemostasis, inflammatory, proliferative, remodeling). During wound healing, collagen attracts cells like fibroblasts and keratinocytes to the wound, stimulating debridement, creating angiogenesis, and reepithelialization. Therefore, providing a natural scaffolding for newly formed collagen fibers and granulation tissue within the wound bed.
There are various collagen technologies and dressing features available globally. The goal of collagen technology dressings is to regulate elevated levels of matrix metalloproteinases (MMPs) found within the extracellular matrix (ECM), which degrade both viable and non-viable tissues. These bioactive dressings chemically bind to the MMPs giving the collagen dressing another collagen source, therefore parting from the body’s natural collagen.
When choosing a collagen dressing, consider the collagen type, processing during manufacturing, conformability, multifunctionality in reducing proteolytic enzymes, and building the scaffold for healing. Collagen dressings can provide anti-infective, anti-inflammatory, antifibrotic, and analgesic properties and promote angiogenesis, returning the body to its normal state and function and providing a foundation for wound healing.