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Advanced Wound Care Product Medifil® II Collagen Particles

Medifil® II Collagen Particles is a Kollagen product that gives a wound both biological and physical qualities. The particles have a large surface area, allowing them to effectively penetrate the wound surface and release the maximum quantity of collagen. Medifil® II is a non-hydrolyzed type 1 bovine native collagen that is 100% non-hydrolyzed. This technology approach developed by Human BioSciences, Inc. protects and retains considerably more native triple helical protein structure, providing for enhanced molecule and scaffold stability during all four phases of wound healing.

Advanced wound care solutions are focused on the wound’s microenvironment and are meant to maintain an ideal moist wound environment. Proper wound healing necessitates a moist wound healing environment. HBS uses a patented manufacturing technology called “Kollagen” to create its native or aka non-hydrolyzed bovine type I collagen product.

Medifil® II Collagen Particles are bioactive material products that interact with the wound microenvironment on a cellular and molecular level, assisting the body’s natural healing process. HBS’ native or aka non-hydrolyzed collagen is the “purest form” of collagen. Non-hydrolyzed collagen preserves a higher percentage of its native triple helix protein structure during wound healing, resulting in increased molecular and scaffold stability. Collagen must maintain its triple helix structure to improve heat endurance, mechanical strength, and the ability to engage in precise interactions with other biomolecules.

Application of Medifil® II Collagen Particles

  • Cleanse the wound with a non cytotoxic wound cleanser, extending to the surrounding skin.
  • Apply Medifil® II particles ¼ inch to the entire wound bed surface, including any deeper areas.
  • Cover the wound with an absorbent dressing to provide an advantageous healing environment.
  • Change the dressing based on the drainage amount.

Features & Benefits of Medifil® II Collagen Particles

  • Absorbs 40-60 times its weight in fluid

  • Accelerates healing

  • Balances the wound microenvironment

  • Higher protein structure of collagen

  • Mimic’s the body’s own collagen

  • Easy pour vial in compliance with infection control


Indications include:

  • Minor wounds (shallow)
  • Major wounds (deep)
  • Arterial ulcers
  • Venous ulcers
  • Diabetic ulcers
  • Pressure wounds
  • Second-degree burns
  • Donor sites
  • Dehisced surgical wounds
  • Traumatic wounds


  • Do not use on third-degree burns
  • Do not use it in patients with bovine sensitivities.


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Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.

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