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What Are SkinTemp® II Collagen Sheets
Advanced wound care requires maintaining a balanced wound microenvironment while supporting the body’s natural healing mechanisms. SkinTemp® II Collagen Sheets are designed to deliver bioactive collagen in a breathable, skin-like format that promotes tissue regeneration, moisture balance, and wound stability across all phases of healing
SkinTemp® II is a Kollagen™ technology product that provides both biological and physical support to the wound bed. Supplied in sheet form, these porous collagen membranes are permeable and breathable, offering fluid control similar to natural skin. The sheets are flexible, pliable, elastic, and durable, allowing easy application across a variety of wound types.
SkinTemp® II is composed of 100 percent non-hydrolyzed type I bovine native collagen. The proprietary Kollagen™ technology process developed by Human BioSciences protects and retains significantly more native triple helical protein structure, ensuring superior molecular stability and scaffold integrity throughout all four phases of wound healing.
Importance of a Moist Wound Healing Environment
Advanced wound care solutions focus on optimizing the wound microenvironment to support predictable healing outcomes. Proper wound healing requires a moist wound healing environment that enables cellular migration, collagen deposition, and angiogenesis.
SkinTemp® II Collagen Sheets absorb excess exudate while maintaining moisture balance, supporting a stable environment for tissue regeneration.
Bioactive Collagen and Healing Support
SkinTemp® II Collagen Sheets are bioactive materials that interact with the wound microenvironment at cellular and molecular levels. Non-hydrolyzed collagen preserves a higher percentage of its native triple helix structure, which is essential for mechanical strength, heat resistance, and precise biomolecular interactions.
Maintaining this structure enhances scaffold stability and supports fibroblast activity, keratinocyte migration, and tissue remodeling.
Application of SkinTemp® II Collagen Sheets
- Cleanse the wound with a non-cytotoxic wound cleanser
- Apply the SkinTemp® II Collagen Sheet directly to the wound bed, including deeper areas when present
- Cover with a large absorbent secondary dressing to maintain an optimal healing environment
- Change the dressing based on the amount of wound drainage
Features and Benefits of SkinTemp® II Collagen Sheets
- Easy to apply and conform to wound surfaces
- Absorbs 40 to 60 times its weight in fluid
- Supports accelerated healing
- Balances the wound microenvironment
- Higher protein structure collagen
- Mimics the body’s natural collagen
- Available in larger sizes including 7 x 7 and 8 x 12
Indications for Use
- Minor wounds
- Major wounds
- Arterial ulcers
- Venous ulcers
- Diabetic ulcers
- Pressure injuries
- Second-degree burns
- Donor sites
- Dehisced surgical wounds
- Traumatic wounds
Warnings and Precautions
Do not use on third-degree burns
Do not use in patients with bovine sensitivities
Learn more at https://humanbiosciences.com. Request samples athttps://humanbiosciences.com/prescription-products/
Human BioSciences, Inc. blog offers education and tips; however, the information provided by this website or company is not a substitute for medical treatment or advice.
FAQ
They are used to support moist wound healing in shallow, deep, and complex wounds.
Sheets provide surface coverage and structural support, making them ideal for flat or shallow wounds.
Yes, they can absorb up to 40 to 60 times their weight in fluid.
Dressing changes depend on wound drainage and clinical assessment.
They should not be used on third-degree burns or in patients with bovine sensitivities.







