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Collagen Dressings used in Conjunction with Negative Pressure Wound Therapy (NPWT)

Complex wounds like arterial ulcers, venous ulcers, diabetic ulcers, and pressure ulcers require a multidisciplinary team working together to impact optimized healing. These wounds are oftentimes a challenge for both the patient and clinician due to the chronicity where there is an inability to heal the wound, risks of infection, and managing the associated systemic disorders. Not to mention, the substantial burden on the healthcare industry with costs exceeding $10 billion annually in North America.

Various modalities are sometimes necessary to achieve healing with chronic or hard-to-heal wounds, as mentioned. Negative pressure wound therapy (NPWT) is a technology that has been used in the management and treatment of surgical and various other wound etiologies. NPWT is a type of therapy that decreases air pressure on the wound by using an application of sub-atmospheric pressure to assist in wound management. NPWT has been shown to enhance healing and improve the progression rate of new tissue formation, decreasing swelling and bacterial burden in wounds.

It has been reported that the use of collagen dressings in conjunction with other treatment modalities like negative pressure wound therapy (NPWT) can help enhance healing. Collagen has been used as a catalyst for wound healing in patients with wound chronicity due to the crucial component of the extracellular (ECM) during healing and tissue remodeling. However, collagen plays a major role in all four phases of wound healing; Hemostasis, Inflammatory, Proliferative, and Remodeling.

When NPWT and collagen dressing treatments are paired together, they help generate new granulation tissue, clearing degenerative fibrous tissue, scaffold osteoblasts, and moving complex wounds towards a healing trajectory. Combining collagen dressings and NPWT requires a 3-day a week dressing change. Wound cleansing, application of the collagen dressing including in deeper areas, NPWT foam dressing application, supports a moist wound healing environment and advantageous wound microenvironment to optimize healing outcomes.

When challenged with chronic or hard-to-heal wounds, it is important to remember that regular monitoring of the wound, along with various treatment modalities may be indicated as appropriate to help shorten the length of healing time and reduce patient suffering.

Human BioSciences, Inc. blog offers education and tips; however,the information provided by this website or company is not a substitute for medical treatment or advice.

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