When the skin is injured, there are three choices for healing. Primary, secondary and tertiary healing paths will be determined by the wound characteristics. Your doctor will help make the best possible choice to facilitate healing. Once the healing intention is determined, the wound will continue to progress through the four phases of healing.
Three types of healing
Four phases of healing
Before the actual wound-healing process begins, the body initiates a phase called hemostasis. Hemostasis aims to stop the bleeding and involves blood clot formation, vasoconstriction, and platelet aggregation. This initial response is vital for the subsequent healing phases to take place effectively. Hemostasis happens normally within a few minutes or hours.
The inflammatory phase is the body’s natural response to tissue injury. It involves the activation of immune cells, the release of inflammatory mediators, and the initiation of the healing process. During this phase, white blood cells clean the wound of debris, bacteria, and foreign substances, while inflammation helps to control infection and prepare the wound for the next phase. There will be mild swelling and redness during this phase which is normal and necessary that should not be confused with signs of infection. An infection will have a much greater response that continues to worsen if left untreated.
New tissue is generated to fill the wound space during the proliferative phase. The wound is rebuilt with the formation of granulation tissue, which consists of new blood vessels, collagen, and fibroblasts. This tissue is not the same as the original tissue but will fill in to form the scar. Epithelial cells at the wound edges begin to migrate, gradually closing the wound. This phase is characterized by the formation of new blood vessels or angiogenesis), collagen synthesis, and wound contraction. Re-epithelialization and proliferation phases are synonymous.
The final phase of wound healing is the remodeling phase. During this phase, the newly formed collagen fibers reorganize and realign themselves, increasing the strength and integrity of the healed tissue. This process can take months to years, and the scar tissue gradually becomes more organized and resembles the surrounding tissue, although never quite gaining full strength.
Wound healing is a complex and dynamic process that involves various cellular and molecular mechanisms. Understanding the different types of wound healing can provide valuable insights into how our bodies repair themselves after an injury. Whether it’s a small cut or a more severe wound, our bodies possess remarkable restorative capabilities. By appreciating the intricacies of wound healing, we can better care for our injuries and support the body’s natural process of regeneration.
What are the types of wound healing?
Wound healing is a complex and fascinating process that occurs when the body’s tissues are damaged. Our bodies have a remarkable ability to repair themselves, and wound healing is a crucial part of this regenerative process. In this article, we will explore the different types of wound healing and understand the mechanisms behind each one. Whether you’ve experienced a minor cut or a more severe injury, this knowledge will help you appreciate the remarkable nature of the healing process.
When the skin is injured, there are three choices for healing. Primary, secondary and tertiary healing paths will be determined by the wound characteristics. Your doctor will help make the best possible choice to facilitate healing. Once the healing intention is determined, the wound will continue to progress through the four phases of healing.
Three types of healing
Four phases of healing
Before the actual wound-healing process begins, the body initiates a phase called hemostasis. Hemostasis aims to stop the bleeding and involves blood clot formation, vasoconstriction, and platelet aggregation. This initial response is vital for the subsequent healing phases to take place effectively. Hemostasis happens normally within a few minutes or hours.
The inflammatory phase is the body’s natural response to tissue injury. It involves the activation of immune cells, the release of inflammatory mediators, and the initiation of the healing process. During this phase, white blood cells clean the wound of debris, bacteria, and foreign substances, while inflammation helps to control infection and prepare the wound for the next phase. There will be mild swelling and redness during this phase which is normal and necessary that should not be confused with signs of infection. An infection will have a much greater response that continues to worsen if left untreated.
New tissue is generated to fill the wound space during the proliferative phase. The wound is rebuilt with the formation of granulation tissue, which consists of new blood vessels, collagen, and fibroblasts. This tissue is not the same as the original tissue but will fill in to form the scar. Epithelial cells at the wound edges begin to migrate, gradually closing the wound. This phase is characterized by the formation of new blood vessels or angiogenesis), collagen synthesis, and wound contraction. Re-epithelialization and proliferation phases are synonymous.
The final phase of wound healing is the remodeling phase. During this phase, the newly formed collagen fibers reorganize and realign themselves, increasing the strength and integrity of the healed tissue. This process can take months to years, and the scar tissue gradually becomes more organized and resembles the surrounding tissue, although never quite gaining full strength.
Wound healing is a complex and dynamic process that involves various cellular and molecular mechanisms. Understanding the different types of wound healing can provide valuable insights into how our bodies repair themselves after an injury. Whether it’s a small cut or a more severe wound, our bodies possess remarkable restorative capabilities. By appreciating the intricacies of wound healing, we can better care for our injuries and support the body’s natural process of regeneration.
©2020 Human Biosciences, Inc. The content presented here is for your information only. It is not a substitute for professional medical advice.
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Mrs. Vann is responsible for branding, design, and public outreach efforts for the company. Mrs. Vann has over five years of experience in the creative design arena. She has spearheaded multiple marketing campaigns, both domestic and international. She also has experience producing several television and live-stage programs. She has a Bachelor’s Degree in Film and Video Studies from George Mason University.
Patent for collagen processing is issued
First collagen veterinary products are developed
Kollagen™ is developed- the world’s first collagen wound care dressings are cleared by the FDA
HBS receives several research grants
New headquarters established in Maryland
HBS is founded by Manoj. K. Jain in Kansas.
Mr. Patel is the Vice President of Operations for Human BioSciences. As such, he is responsible for strategy development for optimal growth, organizing multiple teams and implementing optimal product delivery for the growth of HBS. He has served multiple positions within HBS since 2001, including Operations Manager. With an MBA in Pharmaceutical Healthcare and a Bachelor’s in Pharmaceuticals, Mr. Patel brings deep technical knowledge in collagen product production with a rich history in managing teams.
As the President of Human BioSciences, Dr. Rohan K Jain is responsible for the company’s overall operations, with a focus on research and development. Dr. Jain has supervised and conducted extensive research in the collagen, biomaterials, and protein space, resulting in the release of numerous new products to the market. Prior to his role at HBS, Dr. Jain was a capital markets attorney at Shearman & Sterling LLP. He received his Doctorate in Law and his MBA from New York University; his Bachelor’s degrees in Biomedical Engineering and Materials Science and his Master’s in Engineering Management from Johns Hopkins University. He is a member of the New York and Maryland bars.
Cheryl Carver, LPN, WCC, CWCA, CWCP, DAPWCA, FACCWS is responsible for clinical education and training initiatives for customer accounts. Ms. Carver has amassed a wealth of clinical knowledge and industry experience in her more than 20 years as a board-certified wound care nurse. She has authored over 200 published white papers, ebooks, blogs, and articles for WoundSource and freelance.
Dr. Goebel is responsible for the company’s physical infrastructure and global expansion efforts through partnerships. Prior to joining HBS, Dr. Goebel was Managing Director at the Graf Matuschka Group in Munich, Germany, where he was actively involved in restructuring and privatization in East Germany and Eastern Europe. He was also a member of the American group of the EBRD European Bank for Reconstruction and Development in the privatization of the Russian economy and military complex. He has over forty years’ experience in many different industries including medical devices, pharmacy, and others. Dr. Goebel earned his Doctorate and Postdoctoral degrees in Economics in East Berlin.
Mr. Kumar is responsible for the company’s overall accounting and finance activities with a focus on internal control and taxation.
Mr. Kumar has over 25 years of public and corporate accounting experience. He is a Certified Public Accountant, licensed in the State of Virginia, Maryland, and Washington D.C., and an Enrolled Agent authorized to practice before the Internal Revenue Service. Mr. Kumar is also a Chartered Accountant and fellow member of the Institute of Chartered Accountants of India. Mr. Kumar received his Master’s degree in Commerce from Himalayan University in India.
Mr. Slovick is responsible for all regulatory and quality affairs in the company. Mr. Slovick has worked in regulatory, quality, and clinical services within the medical device and diagnostics industry for nearly 40 years. He founded Methodize Inc., to offer strategic support for approval of medical devices and in vitro diagnostics products. Mr. Slovick has a Bachelor’s degree in Management Information Systems.
Mr. Agarwal is responsible for Corporate Business Development, Sales, and Product Development, both locally and internationally for the company. Mr. Agarwal has over six years of corporate sales and business development experience. He completed his Master of Science in Engineering Management degree from Johns Hopkins University with a technical concentration in Mechanical Engineering. In the past, he has also worked as a fundraising volunteer for three years and thus gained insights in community fundraising and business development. Additionally, he has interned at a manufacturing firm and understood various intricacies involved in manufacturing ranging from the floor level to the supply chain. He has published a paper on Omni Channel Supply Chain and is a certified Lean Six Sigma associate. He has also interned as a business development consultant to a startup for market research and pricing strategies in Israel. Equipped with a combination of management and technical background acquired from his diverse experiences and education, he is perfectly suited to lead the business development efforts for Human BioSciences.